thyroiddisease

A Critical Piece of the Thyroid Puzzle

5 Ways to Support Conversion of T4 to T3💫

For anyone looking to optimize their thyroid function, this is ESSENTIAL.

Your thyroid gland makes hormone in the form of T4, which is then converted into the more active T3 in other areas—especially the liver.

If this conversion is sluggish, you may feel the effects of low thyroid function even if T4 levels are within the normal range.

Here are some ways to support the conversion:

🥗 Liver Support

Since conversion of T4 to T3 happens primarily in the liver, supporting healthy liver function also supports healthy thyroid function.

🌱 Gut Support

The enzyme needed to convert T4 to T3 is also present in the gut wall, so gut health may influence T3 levels.

💊 Nutrient Optimization

T4 to T3 conversion depends on selenium and zinc, found mainly in meats, nuts, and seeds.

🧘‍♀️ Stress Management

Anything the body perceives as stress triggers the release of cortisol. Higher levels of cortisol are associated with more conversion of T4 to reverse T3 (inactive form) rather than the active T3.

🍭 Blood Sugar Balance

Similar to the effect of stress, insulin resistance is associated with more conversion of T4 to reverse T3 (inactive form) rather than the active T3.

Which of these is new to you?

Let me know in the comments ⤵️

Reference

Gierach M, Gierach J, Junik R. Insulin resistance and thyroid disorders. Endokrynol Pol. 2014;65(1):70-76. [link]

Knezevic J, Starchl C, Tmava Berisha A, Amrein K. Thyroid-Gut-Axis: How Does the Microbiota Influence Thyroid Function?. Nutrients. 2020;12(6):1769. Published 2020 Jun 12. [link]

Sinha SR, Prakash P, Keshari JR, Kumari R, Prakash V. Assessment of Serum Cortisol Levels in Hypothyroidism Patients: A Cross-Sectional Study. Cureus. 2023;15(12):e50199. [link]

Hidden Threats to the Thyroid

If you want to optimize thyroid function, avoid these ➡️

Endocrine-Disrupting Chemicals (EDCs) are chemicals that mess with our hormonal systems, including the thyroid gland.

Specific chemicals that are known to disrupt the thyroid are:

🥤 BPA (in plastics)

🧴 Phthalates (in personal care products)

🐟 PCBs (in seafood)

🛋️ PBDBs (flame retardants in furniture & carpets)

Studies show 📚 that some of these chemicals disrupt thyroid hormone production, while others interfere with thyroid hormone transport or receptors.

You can see from this list that these chemicals are everywhere in our daily lives 👎

Still, we can minimize our exposure by choosing foods not packaged in plastics, clean personal care products, and safer seafood.

This is why our holistic approach to thyroid health not only looks at nutrition and how different body systems interact—but also at how we can reduce the body burden of chemicals and environmental toxins.

Reference

Sokal A, Jarmakiewicz-Czaja S, Tabarkiewicz J, Filip R. Dietary Intake of Endocrine Disrupting Substances Presents in Environment and Their Impact on Thyroid Function. Nutrients. 2021;13(3):867. [link]

Could It Be Your Thyroid?

Warning Signs of Thyroid Imbalance ⬇️

But first some basics:

Your thyroid gland is a butterfly-shaped gland at the front of your neck that regulates metabolism (how your body uses energy) but also influences….

▪️ Metabolic rate

▪️ Heart rate

▪️ Blood pressure

▪️ Body temperature

▪️ Gut motility

▪️ Mental function

▪️ Mood

▪️ Menstruation

▪️ Fertility

Signs of an *overactive* thyroid include feeling anxious or irritable, difficulty sleeping, racing heart, shaking hands, clammy skin, sensitivity to heat, unexplained weight loss (or gain), or irregular periods.

Signs of an *underactive* thyroid include feeling tired all the time, mood swings, brain fog, dry skin, hair loss, brittle nails, constipation, sensitivity to cold, unexplained weight gain, or heavy periods.

The only way to know how your thyroid is functioning is to TEST.

Still, thyroid imbalances are sometimes missed by routine screenings, and even when labs are brought into the normal range, I often see patients who still do not feel well.

Watch for my upcoming post all about how functional medicine can help you understand, address, and optimize thyroid function 🙌

Like ❤️ if you found this helpful.