Aging Happens in Bursts (new study!)

This might explain a few things.

A new study tracking 108 Californians between the ages of 25 and 75 found that human aging is not linear! Instead, they found bursts of disruption in molecular markers of aging at 2 points in time:

▪️ Around the age of 44, changes occur that affect the metabolism of lipids, caffeine, and alcohol

▪️ Around the age of 60, changes occur that affect immune function, kidney function, and the metabolism of carbohydrates

The study used the words “waves” and “crests” to describe the moments across the lifespan when aging activities spike. At both the age 44 and age 60 crests, muscle and skin aging also accelerated.

Do you think your body has hit one of these aging bursts?

PMID 39143318

REFERENCE:

Shen X, Wang C, Zhou X, et al. Nonlinear dynamics of multi-omics profiles during human aging. Nat Aging. Published online August 14, 2024. [link]

Surprising Cause of Accelerated Aging

Sugar is making you age faster 💥

Not to be dramatic, but the truth is that sugar spikes cause a biochemical process called glycation…and the production of advanced glycation end products (AGEs).

Turns out that AGEs play a big role in skin aging.

They accumulate in the skin, compromise collagen, and contribute to fine lines, wrinkles, and sagging skin 😩

Sure, glycation is a natural process that increases with age anyway, but diets that are high in sugar or refined carbs without a balance of healthy fats, fiber, and protein accelerate the process.

Is slowing down the aging process a motivating factor for you?

🌱 Get started at our practice through the link in our bio!

Reference

Gkogkolou P, Böhm M. Advanced glycation end products: Key players in skin aging?. Dermatoendocrinol. 2012;4(3):259-270. [link]

A Simple Boost for Healthy Aging 👉

🧐 Check this out ➡️ The first study to look at the long-term effects of protein consumption during midlife!!

Protein is essential for bone and muscle health, both of which can decline with age.

But the results of this study say that “protein intake was significantly associated with higher odds of healthy aging.”

🙌🙌🙌

Plant-based protein was also associated with good mental health status and a lower risk of limitations in physical function.

This was based on data from 48,762 women younger than age 60 who participated in the Nurses’ Health Study.

Want some simple ways to boost protein intake?

🔹 Grab nuts instead of chips.

🔹 Toss chickpeas on your salad.

🔹 Add a high-quality protein powder to your smoothie.

🔹 Spread nut butter on fruit

If you want to see more posts like this on research-backed ways to optimize your health,

Like this post ❤️ and be sure to tap FOLLOW!

Reference

Ardisson Korat AV, Shea MK, Jacques PF, et al. Dietary protein intake in midlife in relation to healthy aging – results from the prospective Nurses’ Health Study cohort. Am J Clin Nut. 2024. Published 2024 Jan 17. [link]

How to Combat the Aging Brain [New Study] 🧠

This one is for anyone who cares about their memory as they age 🧠

🗞️ The just-released COSMOS-Web Study asked this question: Can flavanol supplements benefit the aging brain?

Flavanols are naturally occurring compounds in plant foods that have antioxidant and health-promoting properties, but not everyone eats enough 🍎🍇🍫

Building on over 15 years of research, the current study assigned 3500 healthy older adults to take a daily flavanol supplement (or placebo) for 3 years. The supplement contained 500 mg of flavanols, including 80 mg of epicatechins.

The results?

✅ Memory scores improved slightly for everyone taking the daily flavanol supplement.

✅ Memory scores improved most significantly (by 16%) in those who were consuming a poorer diet and had lower baseline levels of flavanols.

✅ Even more importantly, memory improvement was sustained for at least two more years

Think of it like this:

Just like the developing brain of newborns and small children requires specific nutrients for proper development, so too does the aging brain require specific nutrients for optimal health.

Now we know flavanols are some of those key brain nutrients.

Reference

Brickman AM, Yeung LK, Alschuler DM, et al. Dietary flavanols restore hippocampal-dependent memory in older adults with lower diet quality and lower habitual flavanol consumption. Proc Natl Acad Sci U S A. 2023;120(23):e2216932120. [link]

Sleeping Less than 5 Hours Per Night? Read This.

💤 Sleeping 5 hours or less per night? 

New research on the health of 70,000 men and women in their 50s, 60s, and 70s, showed a link between 5 hours or less per night and disease risk. 

Compared with those who slept 7 hours per night, those who slept only 5:

⬆️ were 20% more likely to be diagnosed with a chronic disease at age 50

⬆️ were 40% more likely to be diagnosed with 2 or more chronic diseases over 25 years

⬆️ had a 25% increased risk of death over 25 years

The study was published in PLOS Medicine. It relates to the series we’re doing this month on circadian rhythms and is a good reminder of how important it is to get a good night’s sleep!

If you need help with sleep, please book an appointment so we can help!

Reference

Séverine Sabia, Aline Dugravot, Damien Léger, et al. Association of sleep duration at age 50, 60, and 70 years with risk of multimorbidity in the UK: 25-year follow-up of the Whitehall II cohort study. PLOS Medicine, 2022; 19 (10): e1004109. [link]